Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20005252 | 0.95 | PDE3B (0.33) | PDE3BPDE3ARPS6KA3 | |
| SCHEMBL20004910 | 0.94 | GRM5 (0.33) | PDE3BPDE3AAKR1C3AKR1C2AKR1B10 | |
| SCHEMBL20005289 | 0.94 | AKR1C3 (0.33) | PDE3BPDE3AAKR1C3AKR1C2AKR1B10 | |
| SCHEMBL20005223 | 0.92 | GRM5 (0.34) | PDE3BPDE3ARPS6KA3 | |
| SCHEMBL20004915 | 0.91 | PDE3B (0.33) | PDE3BPDE3AAKR1C3AKR1C2 | |
| SCHEMBL20006668 | 0.91 | MEN1 (0.35) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL20004795 | 0.90 | GRM5 (0.34) | PDE3BPDE3AAKR1C3AKR1C2AKR1B10 | |
| SCHEMBL20004620 | 0.89 | CYP11B1 (0.31) | — | |
| SCHEMBL20004931 | 0.89 | PDE3B (0.30) | PDE3BPDE3A | |
| SCHEMBL20005243 | 0.89 | PDE9A (0.33) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299439-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC Corporation (JP) | 2018-03-28 | — | — | EP | disclosed |