SCHEMBL200048

SCHEMBL200048

CCO[SiH](CCCNC)OCC

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483472 0.93 EPHX1 (0.42) EPHX1
SCHEMBL15360912 0.91 EPHX1 (0.46) EPHX1
SCHEMBL3452062 0.85 EPHX1 (0.31) EPHX1
SCHEMBL975253 0.83 CYP2C19 (0.38)
SCHEMBL1136261 0.82 EPHX1 (0.41) EPHX1
SCHEMBL6711996 0.81 CYP2C19 (0.36)
SCHEMBL3912318 0.79 CYP2C19 (0.46)
SCHEMBL703482 0.79
SCHEMBL703802 0.79
Dimethylamine SCHEMBL28515915 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8540814-B2 Coatings for corrosion susceptible substrates TRENT UNIVERSITY (CA) 2013-09-24 US claimed
US-20100119837-A1 COATINGS FOR CORROSION SUSCEPTIBLE SUBSTRATES TRENT UNIVERSITY (CA) 2010-05-13 US claimed
EP-3842131-A1 FLUORINATED SILANE SURFACE MODIFIED POLYETHERSULFONE MEMBRANES AND METHOD OF MAKING THEREOF 3M Innovative Properties Company (US) 2021-06-30 EP disclosed
CN-107446135-B Dynamic polymer with dynamic cross-linked structure 翁秋梅 2020-04-10 CN disclosed
EP-2803699-B1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME BRIDGESTONE CORP (JP) 2018-09-12 EP disclosed
US-9623705-B2 Method for producing modified conjugated diene polymer/copolymer, modified conjugated diene polymer/copolymer, and rubber composition and tire using the same BRIDGESTONE CORPORATION (JP) 2017-04-18 US disclosed
EP-2142558-B1 HYDROLYZABLE SILANES OF LOW VOC-GENERATING POTENTIAL AND RESINOUS COMPOSITIONS CONTAINING SAME MOMENTIVE PERFORMANCE MAT INC (US) 2016-10-05 EP disclosed
US-9447208-B2 Rubber composition for tire, vulcanized rubber composition for tire, and tires using same BRIDGESTONE CORPORATION (JP) 2016-09-20 US disclosed
EP-2137198-B1 EPOXYSILANES, PROCESSES FOR THEIR MANUFACTURE AND CURABLE COMPOSITIONS CONTAINING SAME MOMENTIVE PERFORMANCE MAT INC (US) 2016-05-18 EP disclosed
EP-2660244-B1 Organoxysilane compounds having silyl-protected secondary amino group and making method SHINETSU CHEMICAL CO (JP) 2016-02-10 EP disclosed
US-9024051-B2 Organoxysilane compounds having silyl-protected secondary amino group and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-05-05 US disclosed
WO-2009005642-A1 CURABLE SILYL-CONTAINING POLYMER COMPOSITION CONTAINING PAINT ADHESION ADDITIVE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-01-08 WO disclosed
US-20090005498-A1 Curable silyl-containing polymer composition containing paint adhesion additive MOMENTIVE PERFORMANCE MATERIALS INC. 2009-01-01 US disclosed
WO-2008121360-A1 HYDROLYZABLE SILANES OF LOW VOC-GENERATING POTENTIAL AND RESINOUS COMPOSITIONS CONTAINING SAME MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-10-09 WO disclosed
US-20080237537-A1 Hydrolyzable silanes of low VOC-generating potential and resinous compositions containing same MOMENTIVE PERFORMANCE MATERIALS INC. 2008-10-02 US disclosed
WO-2008112150-A1 EPOXYSILANES, PROCESSES FOR THEIR MANUFACTURE AND CURABLE COMPOSITIONS CONTAINING SAME MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-09-18 WO disclosed
US-20080221238-A1 Epoxysilanes, processes for their manufacture and curable compositions containing same MOMENTIVE PERFORMANCE MATERIALS INC. 2008-09-11 US disclosed
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 EP disclosed
US-7235186-B2 Organosilicon compounds comprising cyclodextrin radicals WACKER CHEMIE AG (DE) 2007-06-26 US disclosed
US-20060009592-A1 Organosilicon compounds comprising cyclodextrin radicals WACKER-CHEMIE GMBH (DE) 2006-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080237537-A1 Hydrolyzable silanes of low VOC-generating potential and resinous compositions containing same GSTM1, GSTP1, GSTM2 EPHX1 148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.