Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004363 | 0.81 | PYCR1 (0.57) | PYCR1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22537608 | 0.79 | PYCR1 (0.54) | PYCR1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18714778 | 0.79 | PYCR1 (0.54) | PYCR1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17193942 | 0.79 | PYCR1 (0.62) | PYCR1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16980535 | 0.77 | SIGMAR1 (0.56) | PYCR1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16980543 | 0.77 | PYCR1 (0.61) | PYCR1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16980545 | 0.77 | PYCR1 (0.61) | PYCR1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6894409 | 0.76 | HRH3 (0.58) | PYCR1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14019833 | 0.74 | SIGMAR1 (0.56) | PYCR1SIGMAR1 | |
| SCHEMBL21158890 | 0.74 | HIF1A (0.50) | PYCR1KDM4EMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |