SCHEMBL20005064

SCHEMBL20005064

CC1(F)C=CC=C(COCc2ccc(C#Cc3cc4cccnc4[nH]3)cc2)C1

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SNCA P37840 8/20 0.46
MAPT P10636 4/20 0.46
RIPK1 Q13546 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20005065 0.75 SNCA (0.59) SNCAMAPTRIPK1
SCHEMBL20005050 0.75 SNCA (0.52) SNCAMAPTRIPK1
SCHEMBL22537623 0.74 SNCA (0.57) SNCAMAPTRIPK1
SCHEMBL22537800 0.70 SNCA (0.44) SNCAMAPTRIPK1
SCHEMBL20005009 0.69 SNCA (0.64) SNCAMAPTRIPK1
SCHEMBL20005072 0.68 SNCA (0.68) SNCAMAPTRIPK1
SCHEMBL20005138 0.68 SNCA (0.72) SNCAMAPTRIPK1
SCHEMBL20004519 0.67 SNCA (0.67) SNCAMAPTRIPK1
SCHEMBL20005052 0.66 SNCA (0.64) SNCAMAPTRIPK1
SCHEMBL22537895 0.66 SNCA (0.45) SNCAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3515912-B1 COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES CENTRE NAT RECH SCIENT (FR) 2020-10-14 EP disclosed
WO-2018055316-A1 COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2018-03-29 WO disclosed