⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004652 | 0.65 | MAPT (0.43) | — | |
| SCHEMBL20004616 | 0.51 | SNCA (0.41) | — | |
| SCHEMBL12974939 | 0.49 | L3MBTL1 (0.31) | — | |
| SCHEMBL14161077 | 0.45 | L3MBTL1 (0.33) | — | |
| SCHEMBL14344805 | 0.42 | ALDH1A1 (0.42) | — | |
| SCHEMBL10204663 | 0.41 | PDE4D (0.37) | — | |
| SCHEMBL23810046 | 0.41 | KDM4E (0.33) | — | |
| SCHEMBL14344723 | 0.41 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL18922372 | 0.41 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL736051 | 0.40 | L3MBTL1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |