Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SNCA | P37840 | 3/20 | 0.43 |
| ▸ | APP | P05067 | 4/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004522 | 0.73 | SNCA (0.72) | MAPTSNCAAPPDAOATAD2 | |
| SCHEMBL14053608 | 0.65 | KIF11 (0.51) | MAPTSNCAAPP | |
| SCHEMBL24492765 | 0.62 | DAO (0.49) | MAPTSNCADAOATAD2HRH4 | |
| SCHEMBL29422812 | 0.62 | DAO (0.53) | MAPTSNCADAOATAD2HRH4 | |
| SCHEMBL4278906 | 0.62 | DAO (0.53) | MAPTSNCADAOATAD2HRH4 | |
| SCHEMBL20004553 | 0.60 | SNCA (1.00) | MAPTSNCAAPPDAO | |
| SCHEMBL25775091 | 0.59 | MAPT (0.56) | MAPTSNCADAOATAD2HRH4 | |
| SCHEMBL19995022 | 0.59 | SNCA (0.64) | MAPTSNCADAOATAD2HRH4 | |
| SCHEMBL9396747 | 0.59 | ATAD2 (0.49) | MAPTSNCADAOATAD2HRH4 | |
| SCHEMBL20004597 | 0.58 | SNCA (0.94) | MAPTSNCAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |