⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004676 | 0.73 | SNCA (0.54) | — | |
| SCHEMBL22537744 | 0.71 | SNCA (0.41) | — | |
| SCHEMBL22537755 | 0.65 | — | — | |
| SCHEMBL22537723 | 0.57 | SNCA (0.56) | — | |
| SCHEMBL20004645 | 0.54 | SNCA (0.56) | — | |
| SCHEMBL16496769 | 0.52 | KDM4E (0.42) | — | |
| SCHEMBL21147393 | 0.51 | SNCA (0.43) | — | |
| SCHEMBL14431151 | 0.49 | — | — | |
| SCHEMBL25030272 | 0.49 | MPO (0.51) | — | |
| SCHEMBL23319574 | 0.47 | CA5A (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |