SCHEMBL20005227

SCHEMBL20005227

Cc1ccc(-c2ccc(-c3cc(C)c(C#Cc4cc(F)c(C(F)(F)F)c(F)c4)c(F)c3)c(F)c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.35
AR P10275 1/20 0.34
PDK2 Q15119 1/20 0.32
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
PDE3B Q13370 1/20 0.31
PDE3A Q14432 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20005262 0.94 KIF11 (0.31) KIF11AR
SCHEMBL20005288 0.86 PDE3B (0.32) PDE3BPDE3A
SCHEMBL19999506 0.85 RARB (0.38) KIF11
SCHEMBL20005252 0.84 PDE3B (0.33) PDE3BPDE3A
SCHEMBL19999639 0.84 RARB (0.37)
SCHEMBL20005223 0.84 GRM5 (0.34) PDE3BPDE3A
SCHEMBL13863711 0.83 AR (0.41) KIF11ARPDK2CYP11B1CYP11B2
SCHEMBL14234532 0.83 AR (0.41) KIF11ARPDK2CYP11B1CYP11B2
SCHEMBL20004910 0.83 GRM5 (0.33) PDE3BPDE3A
SCHEMBL20005249 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3299439-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC Corporation (JP) 2018-03-28 EP disclosed