Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.34 |
| ▸ | ACHE | P22303 | 7/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.30 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18950854 | 0.79 | EPHX1 (0.39) | EPHX1ACHEMMP2MEN1HTT | |
| SCHEMBL20005340 | 0.79 | CASP2 (0.43) | EPHX1ACHEMMP2MEN1KMT2A | |
| SCHEMBL19631511 | 0.75 | EPHX1 (0.42) | EPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL27253956 | 0.73 | EPHX1 (0.43) | EPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL20123226 | 0.72 | EPHX1 (0.47) | EPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL21393320 | 0.72 | EPHX1 (0.47) | EPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL7796308 | 0.69 | — | — | |
| SCHEMBL20785730 | 0.69 | CASP2 (0.32) | EPHX1 | |
| SCHEMBL25549544 | 0.69 | EPHX1 (0.34) | EPHX1ACHEMMP2MEN1HTT | |
| SCHEMBL18559997 | 0.68 | CNR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018054959-A1 | COMPOUNDS FOR TREATMENT OF LIPOPROTEIN METABOLISM DISORDERS | AARHUS UNIVERSITET (DK) | 2018-03-29 | — | — | WO | disclosed |