Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 11/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20123226 | 1.00 | EPHX1 (0.47) | EPHX1ZDHHC20ZDHHC2CASP2NAAA | |
| SCHEMBL27253956 | 0.98 | EPHX1 (0.43) | EPHX1ZDHHC20ZDHHC2CASP2NAAA | |
| SCHEMBL18950854 | 0.92 | EPHX1 (0.39) | EPHX1ZDHHC20ZDHHC2 | |
| SCHEMBL24488462 | 0.84 | TDP1 (0.33) | EPHX1 | |
| SCHEMBL25720915 | 0.84 | EPHX1 (0.38) | EPHX1 | |
| SCHEMBL19631511 | 0.83 | EPHX1 (0.42) | EPHX1ZDHHC20ZDHHC2CASP2NAAA | |
| SCHEMBL24950632 | 0.82 | FFAR1 (0.30) | — | |
| SCHEMBL19143353 | 0.81 | ADRA1A (0.36) | — | |
| SCHEMBL23175607 | 0.79 | MEN1 (0.32) | EPHX1 | |
| SCHEMBL21236727 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183245-A1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2019-09-26 | — | — | WO | disclosed |