Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27443087 | 0.85 | HSD17B10 (0.42) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL27439612 | 0.85 | HSD17B10 (0.42) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL27516238 | 0.85 | HSD17B10 (0.42) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL27707074 | 0.83 | GPR119 (0.41) | CHRM2CHRM1CHRM3HSD17B10PREP | |
| SCHEMBL23863690 | 0.82 | CHRM2 (0.47) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL21360452 | 0.82 | CHRM2 (0.44) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL25568135 | 0.82 | CHRM2 (0.44) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL17519842 | 0.82 | CHRM2 (0.44) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL15018794 | 0.82 | CHRM2 (0.44) | CHRM2CHRM1CHRM3HSD17B10HPGD | |
| SCHEMBL17012875 | 0.82 | CHRM2 (0.44) | CHRM2CHRM1CHRM3HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111471059-B | PDE9 inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-12-02 | — | — | CN | disclosed |
| WO-2018056854-A1 | BLOOD-BRAIN BARRIER-PENETRANT DOPAMINE-B-HYDROXYLASE INHIBITORS | BIAL - PORTELA & Cª, S.A. (PT) | 2018-03-29 | — | — | WO | disclosed |