SCHEMBL27439612

SCHEMBL27439612

CO[C@H]1CCN1C(=O)OC(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.42
CHRM2 P08172 1/20 0.42
CHRM1 P11229 1/20 0.42
CHRM3 P20309 1/20 0.42
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
USP2 O75604 1/20 0.41
RECQL P46063 1/20 0.40
EPHX1 P07099 1/20 0.40
PREP P48147 1/20 0.38
ALDH1A1 P00352 1/20 0.38
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27516238 1.00 HSD17B10 (0.42) HSD17B10CHRM2CHRM1CHRM3HPGD
SCHEMBL27443087 1.00 HSD17B10 (0.42) HSD17B10CHRM2CHRM1CHRM3HPGD
SCHEMBL925960 0.89 HSD17B10 (0.50) HSD17B10HPGDSMN1; SMN2USP2RECQL
SCHEMBL9977242 0.89 HSD17B10 (0.50) HSD17B10HPGDSMN1; SMN2USP2RECQL
SCHEMBL14457242 0.89 HSD17B10 (0.50) HSD17B10HPGDSMN1; SMN2USP2RECQL
SCHEMBL28516773 0.88 HPGD (0.49) HSD17B10HPGDSMN1; SMN2USP2RECQL
SCHEMBL28100905 0.88 HPGD (0.49) HSD17B10HPGDSMN1; SMN2USP2RECQL
Methyl Alcohol SCHEMBL72605 0.88 HSD17B10 (0.49) HSD17B10HPGDSMN1; SMN2USP2RECQL
SCHEMBL20005993 0.85 CHRM2 (0.41) HSD17B10CHRM2CHRM1CHRM3HPGD
SCHEMBL27707074 0.84 GPR119 (0.41) HSD17B10CHRM2CHRM1CHRM3PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106795171-A Antibacterial basic biaromatic derivatives with aminoalkoxy substitution 埃科特莱茵药品有限公司 2017-05-31 CN disclosed
CN-103131330-B Composition for polishing and use its Ginding process FUJIMI INC. (JP) 2015-09-23 CN disclosed
CN-103131330-A Polishing composition and polishing method using the same FUJIMI INC 2013-06-05 CN disclosed
CN-102216289-A Nicotinic acetylcholine receptor ligands and uses thereof PSYCHOGENICS INC 2011-10-12 CN disclosed
CN-101003513-A Compound in quinazoline class or its pharmaceutical salt preparation method, and medical usage SUN PIAOYANG (CN) 2007-07-25 CN disclosed
CN-1125064-C 3-pyridyl enantiomers and their use as analgesics ABBOTT LAB (US) 2003-10-22 CN disclosed
CN-1245496-A 3-pyridyl enantiomers and their use as analgesics ABBOTT LAB (US) 2000-02-23 CN disclosed