Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRACR2A | Q9BSW2 | 14/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626659 | 0.82 | CRACR2A (0.56) | CRACR2APTGS2PTGS1ORAI1KDM4E | |
| SCHEMBL1880912 | 0.82 | CRACR2A (0.56) | CRACR2APTGS2PTGS1ORAI1KDM4E | |
| SCHEMBL1667944 | 0.82 | CRACR2A (0.56) | CRACR2APTGS2ORAI1KDM4EALDH1A1 | |
| SCHEMBL20006306 | 0.81 | CRACR2A (0.61) | CRACR2APTGS2PTGS1ORAI1 | |
| SCHEMBL30785286 | 0.78 | CRACR2A (0.56) | CRACR2APTGS2ORAI1 | |
| SCHEMBL30677012 | 0.78 | CRACR2A (0.55) | CRACR2APTGS2ORAI1 | |
| SCHEMBL30677204 | 0.78 | CRACR2A (0.53) | CRACR2AORAI1 | |
| SCHEMBL30785292 | 0.78 | CRACR2A (0.53) | CRACR2APTGS2ORAI1KDM4EALDH1A1 | |
| SCHEMBL1668441 | 0.77 | CRACR2A (0.65) | CRACR2APTGS2ORAI1 | |
| SCHEMBL537516 | 0.77 | PTGS2 (0.55) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299361-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL | Rhizen Pharmaceuticals S.A. (CH) | 2018-03-28 | — | — | EP | disclosed |