Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 4/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20006658 | 0.86 | ESR1 (0.50) | PPARAESR1ESR2ACHELMNA | |
| SCHEMBL20006517 | 0.82 | ESR1 (0.56) | PPARAESR1ESR2ACHELMNA | |
| SCHEMBL1129752 | 0.73 | ESR1 (0.87) | PPARAESR1ESR2ACHELMNA | |
| SCHEMBL14760430 | 0.73 | ESR1 (0.87) | PPARAESR1ESR2ACHELMNA | |
| SCHEMBL14173047 | 0.72 | PPARA (0.55) | PPARAESR1ESR2ACHELMNA | |
| SCHEMBL10899114 | 0.72 | ACHE (0.79) | PPARAESR1ESR2ACHELMNA | |
| SCHEMBL10942581 | 0.72 | ACHE (0.79) | PPARAESR1ESR2ACHELMNA | |
| SCHEMBL12893277 | 0.71 | ESR1 (0.62) | PPARAESR1ESR2ACHELMNA | |
| SCHEMBL17523062 | 0.70 | ESR1 (0.59) | PPARAESR1ESR2ACHELMNA | |
| SCHEMBL19268516 | 0.70 | ESR1 (0.59) | PPARAESR1ESR2ACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2738611-B1 | Positively chargeable monolayer electrophotographic photosensitive member and image forming apparatus | KYOCERA DOCUMENT SOLUTIONS INC (JP) | 2018-03-28 | — | — | EP | disclosed |