Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12751501 | 0.82 | ADORA3 (0.37) | ESR1ESR2ADORA3SLC6A4ALDH1A1 | |
| SCHEMBL20006378 | 0.82 | PPARA (0.52) | ESR1ESR2ADORA3ALDH1A1L3MBTL1 | |
| SCHEMBL13979409 | 0.79 | ESR1 (0.63) | ESR1ESR2ADORA3SLC6A4ALDH1A1 | |
| SCHEMBL14143026 | 0.79 | ESR1 (0.57) | ESR1ESR2ADORA3SLC6A4ALDH1A1 | |
| SCHEMBL8760127 | 0.76 | ESR2 (0.71) | ESR1ESR2ADORA3SLC6A4ALDH1A1 | |
| SCHEMBL7026652 | 0.76 | ESR1 (0.50) | ESR1ESR2ADORA3SLC6A4ALDH1A1 | |
| SCHEMBL21085480 | 0.75 | ESR1 (0.77) | ESR1ESR2ADORA3SLC6A4ALDH1A1 | |
| SCHEMBL18773 | 0.74 | ESR2 (1.00) | ESR1ESR2ADORA3SLC6A4ALDH1A1 | |
| SCHEMBL11154712 | 0.74 | ESR2 (1.00) | ESR1ESR2ADORA3SLC6A4ALDH1A1 | |
| SCHEMBL13379654 | 0.74 | ESR2 (1.00) | ESR1ESR2ADORA3SLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2738611-B1 | Positively chargeable monolayer electrophotographic photosensitive member and image forming apparatus | KYOCERA DOCUMENT SOLUTIONS INC (JP) | 2018-03-28 | — | — | EP | disclosed |