Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRACR2A | Q9BSW2 | 14/20 | 0.46 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.37 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.35 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20006573 | 0.86 | CRACR2A (0.59) | CRACR2A | |
| SCHEMBL28240593 | 0.80 | UBE2T (0.55) | UBE2TSLC34A1 | |
| SCHEMBL18171821 | 0.72 | NOTUM (0.40) | — | |
| SCHEMBL20006257 | 0.72 | CRACR2A (0.64) | CRACR2A | |
| SCHEMBL20006441 | 0.69 | CRACR2A (0.58) | CRACR2AKCNJ6KCNJ3 | |
| SCHEMBL28073516 | 0.68 | CRACR2A (0.53) | CRACR2A | |
| SCHEMBL26739745 | 0.66 | GLS (0.36) | — | |
| SCHEMBL20080575 | 0.66 | CRACR2A (0.58) | CRACR2A | |
| SCHEMBL20006247 | 0.66 | CRACR2A (0.55) | CRACR2AKCNJ6KCNJ3KCNJ5 | |
| SCHEMBL25956087 | 0.66 | PDE10A (0.38) | CRACR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299361-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL | Rhizen Pharmaceuticals S.A. (CH) | 2018-03-28 | — | — | EP | disclosed |