SCHEMBL20006611

SCHEMBL20006611

CC(C)C(=O)NCCCC[C@H](N)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.54
GNAI3 P08754 1/20 0.51
GNAO1 P09471 1/20 0.51
GNAI1 P63096 1/20 0.51
GSR P00390 1/20 0.50
NOD1 Q9Y239 1/20 0.49
OTC P00480 1/20 0.49
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
KMT2A Q03164 1/20 0.46
RRM1 P23921 1/20 0.46
ARG2 P78540 4/20 0.46
ARG1 P05089 3/20 0.46
NOS2 P35228 4/20 0.45
NOS1 P29475 3/20 0.45
NOS3 P29474 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
TSHR P16473 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17451629 1.00 DPP7 (0.54) DPP7GNAI3GNAO1GNAI1GSR
SCHEMBL2234222 0.95 OTC (0.54) DPP7GNAI3GNAO1GNAI1GSR
SCHEMBL2234214 0.95 OTC (0.54) DPP7GNAI3GNAO1GNAI1GSR
SCHEMBL20085606 0.89 DPP7 (0.54) DPP7GNAI3GNAO1GNAI1GSR
SCHEMBL19738538 0.88 DPP7 (0.53) DPP7GNAI3GNAO1GNAI1GSR
SCHEMBL5666448 0.88 DPP7 (0.53) DPP7GNAI3GNAO1GNAI1GSR
SCHEMBL1768888 0.87 GSR (0.43) DPP7GSROTCCYP2D6CYP2C9
SCHEMBL1768887 0.87 GSR (0.43) DPP7GSROTCCYP2D6CYP2C9
SCHEMBL22689723 0.86 DPP7 (0.51) DPP7GNAI3GNAO1GNAI1GSR
SCHEMBL22689791 0.86 DPP7 (0.51) DPP7GNAI3GNAO1GNAI1GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018057-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases JANSSEN BIOTECH, INC. (US) 2024-06-25 US claimed
US-20220402983-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES JANSSEN BIOTECH, INC. 2022-12-22 US claimed
EP-4090669-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES Janssen Biotech, Inc. (US) 2022-11-23 EP claimed
CN-115279782-A Peptide inhibitors of interleukin-23 receptor and their use for the treatment of inflammatory diseases 詹森生物科技公司 2022-11-01 CN claimed
US-20250327074-A1 THE RARE CODON RECODING PLATFORM FOR NONCANONICAL AMINO ACIDS INCORPORATION IN MAMMALIAN CELLS SHAOXING INSTITUTE, ZHEJIANG UNIVERSITY (CN) 2025-10-23 US disclosed
EP-4613761-A9 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES Janssen Biotech, Inc. (US) 2025-10-22 EP disclosed
EP-4613761-A2 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES Janssen Biotech, Inc. (US) 2025-09-10 EP disclosed
EP-4090670-B1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES JANSSEN BIOTECH INC (US) 2025-06-04 EP disclosed
US-20240383954-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES JANSSEN BIOTECH INC (US) 2024-11-21 US disclosed
US-12018057-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases JANSSEN BIOTECH, INC. (US) 2024-06-25 US disclosed
US-20240150405-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES JANSSEN BIOTECH INC (US) 2024-05-09 US disclosed
US-20240059753-A1 COMPOSITIONS INCLUDING MULTI-AGONIST PEPTIDES AND METHODS OF MANUFACTURE AND USE PEP2TANGO THERAPEUTICS INC. 2024-02-22 US disclosed
US-20230203100-A1 COMPOSITIONS INCLUDING MULTI-AGONIST PEPTIDES AND METHODS OF MANUFACTURE AND USE PEP2TANGO THERAPEUTICS INC. 2023-06-29 US disclosed
US-20230129095-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS, INC. (US) 2023-04-27 US disclosed
US-20220402983-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES JANSSEN BIOTECH, INC. 2022-12-22 US disclosed
EP-4090669-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES Janssen Biotech, Inc. (US) 2022-11-23 EP disclosed
CN-115279782-A Peptide inhibitors of interleukin-23 receptor and their use for the treatment of inflammatory diseases 詹森生物科技公司 2022-11-01 CN disclosed
US-10221309-B2 Latex functionalized with structural units of an amino acid ROHM AND HAAS COMPANY (US) 2019-03-05 US disclosed
US-20180086909-A1 LATEX FUNCTIONALIZED WITH STRUCTURAL UNITS OF AN AMINO ACID ROHM AND HAAS COMPANY 2018-03-29 US disclosed
EP-3299400-A1 LATEX FUNCTIONALIZED WITH STRUCTURAL UNITS OF AN AMINO ACID Rohm and Haas Company (US) 2018-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230129095-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, VIP DPP7 358/4885GNAI3 551/4885GNAO1 3649/4885
US-20230203100-A1 COMPOSITIONS INCLUDING MULTI-AGONIST PEPTIDES AND METHODS OF MANUFACTURE AND USE IAPP, GPR119, GIPR DPP7 161/4885GNAI3 372/4885GNAO1 365/4885
US-20220402983-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, VIP DPP7 358/4885GNAI3 551/4885GNAO1 3649/4885
US-20240150405-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, VIP DPP7 358/4885GNAI3 551/4885GNAO1 3649/4885
US-20240059753-A1 COMPOSITIONS INCLUDING MULTI-AGONIST PEPTIDES AND METHODS OF MANUFACTURE AND USE IAPP, GPR119, GIPR DPP7 161/4885GNAI3 372/4885GNAO1 365/4885
US-12018057-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases IL23R, IL1RN, VIP DPP7 358/4885GNAI3 551/4885GNAO1 3649/4885
US-20240383954-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, VIP DPP7 358/4885GNAI3 551/4885GNAO1 3649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.