SCHEMBL20006675

SCHEMBL20006675

Cc1cc(-c2ccccc2)cc(F)c1C#Cc1cc(F)c(C(F)(F)Oc2cc(F)c(F)c(F)c2)c(F)c1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
EPM2A O95278 1/20 0.31
PTPRC P08575 1/20 0.31
PTPN2 P17706 1/20 0.31
PTPN1 P18031 1/20 0.31
PTPRG P23470 1/20 0.31
ACP1 P24666 1/20 0.31
PTPN6 P29350 1/20 0.31
PTPN7 P35236 1/20 0.31
PTPN9 P43378 1/20 0.31
DUSP3 P51452 1/20 0.31
PTPN11 Q06124 1/20 0.31
PTPN13 Q12923 1/20 0.31
DUSP22 Q9NRW4 1/20 0.31
CDC14A Q9UNH5 1/20 0.31
PTPN22 Q9Y2R2 1/20 0.31
KAT6A Q92794 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20006921 0.96 MEN1 (0.30) MEN1KMT2AATML3MBTL1
SCHEMBL20006858 0.92 EPM2A (0.30) EPM2APTPRCPTPN2PTPN1PTPRG
SCHEMBL19999358 0.91
SCHEMBL20006682 0.90
SCHEMBL19999563 0.89
SCHEMBL19999477 0.87
SCHEMBL20006717 0.87 TNKS (0.30)
SCHEMBL20006866 0.87 KIF11 (0.31)
SCHEMBL20006859 0.87 ALOX5AP (0.30)
SCHEMBL20006838 0.84 TNKS (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10208249-B2 Liquid crystal compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2019-02-19 US disclosed
US-20180086979-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-03-29 US disclosed