SCHEMBL20006700

SCHEMBL20006700

c1ccc(-c2nc(Sc3nc(-c4ccccn4)n4ccccc34)c3ccccn23)nc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.47
BRD2 P25440 1/20 0.47
BRD3 Q15059 1/20 0.47
BAZ2B Q9UIF8 1/20 0.47
BAZ2A Q9UIF9 1/20 0.47
NPC1 O15118 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
TP53 P04637 2/20 0.41
TSHR P16473 1/20 0.41
PDE10A Q9Y233 1/20 0.41
KDM4E B2RXH2 6/20 0.39
LMNA P02545 3/20 0.39
CCR1 P32246 2/20 0.39
CCR5 P51681 2/20 0.39
CCR8 P51685 2/20 0.39
CYP1A2 P05177 1/20 0.39
POLB P06746 1/20 0.39
METAP1 P53582 1/20 0.39
BLM P54132 1/20 0.39
HIF1A Q16665 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22406353 0.83 BRD4 (0.44) BRD4BRD2BRD3BAZ2BBAZ2A
SCHEMBL23430642 0.79 SMN1; SMN2 (0.46) BRD4BRD2BRD3BAZ2BBAZ2A
SCHEMBL17023904 0.78 KDM4E (0.47) BRD4BRD2BRD3BAZ2BBAZ2A
SCHEMBL17023894 0.78 GAA (0.50) BRD4BRD2BRD3BAZ2BBAZ2A
SCHEMBL19994319 0.78 BRD4 (0.43) BRD4BRD2BRD3BAZ2BBAZ2A
SCHEMBL17023897 0.78 KDM4E (0.50) BRD4BRD2BRD3BAZ2BBAZ2A
SCHEMBL17023905 0.77 BRD4 (0.43) BRD4BRD2BRD3BAZ2BBAZ2A
SCHEMBL17023877 0.77 GAA (0.46) BRD4BRD2BRD3BAZ2BBAZ2A
SCHEMBL25787087 0.77 KMT2A (0.56) BRD4BRD2BRD3BAZ2BBAZ2A
SCHEMBL4497771 0.75 BRD4 (0.50) BRD4BRD2BRD3BAZ2BBAZ2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11679996-B2 Ferro-cavitation processes for target metal separation NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2023-06-20 US disclosed
US-20220169541-A1 FERRO-CAVITATION PROCESSES FOR TARGET METAL SEPARATION NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2022-06-02 US disclosed
US-20210087079-A1 FERRO-CAVITATION PROCESSES FOR TARGET METAL SEPARATION NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2021-03-25 US disclosed
WO-2018053630-A1 FERRO-CAVITATION PROCESSES FOR TARGET METAL SEPARATION NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2018-03-29 WO disclosed