SCHEMBL20006716

SCHEMBL20006716

CCCc1ccc(-c2ccc(-c3cc(F)c(C#Cc4ccc(-c5cc(F)c(C)cc5F)cc4)c(CC)c3)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.33
RARB P10826 3/20 0.33
ACACB O00763 2/20 0.32
RARA P10276 1/20 0.32
RARG P13631 1/20 0.32
ALOX5 P09917 1/20 0.30
MCL1 Q07820 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20004893 0.89 PTGS2 (0.34)
SCHEMBL19999584 0.87 RARB (0.40) FFAR1RARBACACBRARARARG
SCHEMBL19999491 0.81 ACACB (0.47) RARBACACBRARA
SCHEMBL19999528 0.80 RARB (0.38) FFAR1RARBACACBALOX5
SCHEMBL19999429 0.78 RARB (0.43) FFAR1RARBRARARARG
SCHEMBL20005215 0.78 HRH3 (0.34) FFAR1RARBRARARARGALOX5
SCHEMBL25548582 0.78 FFAR1 (0.42) FFAR1RARBACACBRARARARG
SCHEMBL19999397 0.77 FFAR1 (0.40) FFAR1RARBACACBRARARARG
SCHEMBL20006853 0.77 FFAR1 (0.40) FFAR1RARBACACBRARARARG
SCHEMBL20006828 0.77 RARB (0.39) FFAR1RARBACACBALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10208249-B2 Liquid crystal compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2019-02-19 US disclosed
US-20180086979-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-03-29 US disclosed