Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HMGCR | P04035 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13625815 | 0.79 | HMGCR (0.55) | LMNAMAPTXBP1HIF1AHMGCR | |
| SCHEMBL12520531 | 0.76 | TYR (0.56) | LMNAMAPTXBP1HIF1AHMGCR | |
| SCHEMBL1270868 | 0.75 | ALOX5 (0.56) | LMNAMAPTHMGCRTYRALOX5 | |
| SCHEMBL15177138 | 0.73 | ALOX5 (0.59) | LMNAMAPTTYRALOX5ALDH1A1 | |
| SCHEMBL12063304 | 0.73 | EPHX2 (0.44) | LMNAMAPTXBP1HIF1AHPGD | |
| SCHEMBL12063308 | 0.73 | TYR (0.39) | LMNAMAPTXBP1HIF1ATYR | |
| SCHEMBL364672 | 0.72 | ESR1 (0.53) | LMNAMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL20628898 | 0.71 | IDO1 (0.43) | KCNH2KDM4E | |
| SCHEMBL5326448 | 0.71 | TYR (0.37) | LMNAMAPTXBP1HIF1ATYR | |
| SCHEMBL5326452 | 0.71 | TYR (0.37) | LMNAMAPTXBP1HIF1ATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299364-A1 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2018-03-28 | — | — | EP | disclosed |