Tetrabuthylammonium

Tetrabuthylammonium

SCHEMBL2000679

CCCC[N+](CCCC)(CCCC)CCCC.O=Cc1ccc([O-])cc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A1 O15245 3/20 0.43
ALDH1A1 P00352 5/20 0.40
ALDH1A3 P47895 2/20 0.40
ALDH3A1 P30838 1/20 0.40
SLC22A2 O15244 1/20 0.38
CYP2A6 P11509 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
ALOX12 P18054 1/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TYR P14679 1/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP2A13 Q16696 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Hydroxybenzaldehyde SCHEMBL1998646 0.79 ALDH1A1 (0.40) ALDH1A1ALDH1A3ALDH3A1CYP2A6SMN1; SMN2
Tetrabuthylammonium SCHEMBL6431277 0.77 SLC22A1 (0.50) SLC22A1ALDH1A1SLC22A2SMN1; SMN2LMNA
Tetrabuthylammonium SCHEMBL29130245 0.77 ALDH1A1 (0.37) SLC22A1ALDH1A1ALDH1A3ALDH3A1SMN1; SMN2
Tetrabuthylammonium SCHEMBL28464494 0.76 SLC22A1 (0.48) SLC22A1ALDH1A1SLC22A2SMN1; SMN2TP53
Tetrabuthylammonium SCHEMBL11884927 0.76 SLC22A1 (0.48) SLC22A1ALDH1A1SLC22A2SMN1; SMN2TP53
Tetrabuthylammonium SCHEMBL887137 0.75 SLC22A1 (0.52) SLC22A1ALDH1A1SLC22A2SMN1; SMN2TP53
Tetrabuthylammonium SCHEMBL16968724 0.74 MAPT (0.49) SLC22A1ALDH1A1SMN1; SMN2LMNAMAPT
4-Hydroxybenzaldehyde SCHEMBL10956449 0.73 CYP2A6 (0.50) ALDH1A1ALDH1A3ALDH3A1CYP2A6SMN1; SMN2
Tetrabuthylammonium SCHEMBL7890102 0.73 SLC22A1 (0.44) SLC22A1ALDH1A1SLC22A2SMN1; SMN2LMNA
Tetrabuthylammonium SCHEMBL105861 0.71 SLC22A1 (0.67) SLC22A1ALDH1A1SLC22A2SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1742976-B1 LOW-VISCOSITY ALLOPHANATES HAVING ACTINICALLY HARDENABLE GROUPS BAYER MATERIALSCIENCE AG (DE) 2010-09-15 EP claimed
EP-1727846-B1 PRODUCTION OF NOVEL RADIATION-HARDENING BINDING AGENTS BAYER MATERIALSCIENCE AG (DE) 2009-09-16 EP claimed
US-7381785-B2 Preparation of new radiation-curing binders BAYER METERIALSCIENCE AG (DE) 2008-06-03 US claimed
US-7361723-B2 Low-viscosity allophanates containing actinically curable groups BAYER MATERIALSCIENCE AG (DE) 2008-04-22 US claimed
US-20050209427-A1 Low-viscosity allophanates containing actinically curable groups BAYER MATERIALSCIENCE AG 2005-09-22 US claimed
US-20050209361-A1 Preparation of new radiation-curing binders BAYER MATERIALSCIENCE AG 2005-09-22 US claimed
US-7960446-B2 binders containing allophanate groups having active double bonds; reaction with uretdiones; quaternary ammonium phenoxide catalyst; polyurethane coatings BAYER MATERIALSCIENCE AG (DE) 2011-06-14 US disclosed
EP-1727846-B1 PRODUCTION OF NOVEL RADIATION-HARDENING BINDING AGENTS BAYER MATERIALSCIENCE AG (DE) 2009-09-16 EP disclosed
US-20080214691-A1 Low-viscosity allophanates containing actinically curable groups ALLNEX NETHERLANDS B.V. (NL) 2008-09-04 US disclosed
US-7381785-B2 Preparation of new radiation-curing binders BAYER METERIALSCIENCE AG (DE) 2008-06-03 US disclosed
US-7361723-B2 Low-viscosity allophanates containing actinically curable groups BAYER MATERIALSCIENCE AG (DE) 2008-04-22 US disclosed
US-20050209427-A1 Low-viscosity allophanates containing actinically curable groups BAYER MATERIALSCIENCE AG 2005-09-22 US disclosed
US-20050209361-A1 Preparation of new radiation-curing binders BAYER MATERIALSCIENCE AG 2005-09-22 US disclosed