4-Hydroxybenzaldehyde

4-Hydroxybenzaldehyde

SCHEMBL1998646

CCCC[P+](CCCC)(CCCC)CCCC.O=Cc1ccc([O-])cc1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
ALDH1A3 P47895 3/20 0.40
ALDH3A1 P30838 2/20 0.40
DNM1 Q05193 2/20 0.39
TYR P14679 1/20 0.38
CYP2A6 P11509 3/20 0.38
BDKRB2 P30411 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP2A13 Q16696 1/20 0.34
HSD17B10 Q99714 1/20 0.33
ALDH5A1 P51649 1/20 0.33
ABAT P80404 1/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrabuthylammonium SCHEMBL2000679 0.79 SLC22A1 (0.43) ALDH1A1ALDH1A3ALDH3A1TYRCYP2A6
Phenol SCHEMBL126078 0.75 DNM1 (0.46) ALDH1A1DNM1BDKRB2KDM4E
4-Hydroxybenzaldehyde SCHEMBL7255436 0.73 CYP2A6 (0.50) ALDH1A1ALDH1A3ALDH3A1TYRCYP2A6
4-Hydroxybenzaldehyde SCHEMBL10956449 0.73 CYP2A6 (0.50) ALDH1A1ALDH1A3ALDH3A1TYRCYP2A6
SCHEMBL846594 0.73 TYR (0.53) ALDH1A1ALDH1A3ALDH3A1TYRCYP2A6
SCHEMBL10708117 0.71 ALDH1A3 (0.51) ALDH1A1ALDH1A3ALDH3A1TYRCYP2A6
Formic Acid SCHEMBL237482 0.71 DNM1 (0.57) ALDH1A1DNM1BDKRB2SMN1; SMN2MAPT
SCHEMBL16612380 0.70 NR1I2 (0.49) ALDH1A1ALDH1A3ALDH3A1TYRCYP2A6
SCHEMBL8192949 0.70 ALDH1A3 (0.55) ALDH1A1ALDH1A3ALDH3A1TYRCYP2A6
SCHEMBL9490700 0.69 ALDH1A1 (0.41) ALDH1A1ALDH1A3ALDH3A1TYRCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1742976-B1 LOW-VISCOSITY ALLOPHANATES HAVING ACTINICALLY HARDENABLE GROUPS BAYER MATERIALSCIENCE AG (DE) 2010-09-15 EP claimed
EP-1727846-B1 PRODUCTION OF NOVEL RADIATION-HARDENING BINDING AGENTS BAYER MATERIALSCIENCE AG (DE) 2009-09-16 EP claimed
US-7381785-B2 Preparation of new radiation-curing binders BAYER METERIALSCIENCE AG (DE) 2008-06-03 US claimed
US-7361723-B2 Low-viscosity allophanates containing actinically curable groups BAYER MATERIALSCIENCE AG (DE) 2008-04-22 US claimed
US-20050209427-A1 Low-viscosity allophanates containing actinically curable groups BAYER MATERIALSCIENCE AG 2005-09-22 US claimed
US-20050209361-A1 Preparation of new radiation-curing binders BAYER MATERIALSCIENCE AG 2005-09-22 US claimed
US-7960446-B2 binders containing allophanate groups having active double bonds; reaction with uretdiones; quaternary ammonium phenoxide catalyst; polyurethane coatings BAYER MATERIALSCIENCE AG (DE) 2011-06-14 US disclosed
US-20080214691-A1 Low-viscosity allophanates containing actinically curable groups ALLNEX NETHERLANDS B.V. (NL) 2008-09-04 US disclosed
US-7381785-B2 Preparation of new radiation-curing binders BAYER METERIALSCIENCE AG (DE) 2008-06-03 US disclosed
US-7361723-B2 Low-viscosity allophanates containing actinically curable groups BAYER MATERIALSCIENCE AG (DE) 2008-04-22 US disclosed
US-20050209427-A1 Low-viscosity allophanates containing actinically curable groups BAYER MATERIALSCIENCE AG 2005-09-22 US disclosed
US-20050209361-A1 Preparation of new radiation-curing binders BAYER MATERIALSCIENCE AG 2005-09-22 US disclosed