Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.50 |
| ▸ | TUBB | P07437 | 5/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.50 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625442 | 0.86 | TUBB1 (0.58) | TUBB1MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL23734449 | 0.84 | TUBB1 (0.55) | TUBB1MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL3022881 | 0.82 | TUBB1 (0.55) | TUBB1MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL6859776 | 0.81 | TPMT (0.50) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL24147879 | 0.80 | MEN1 (0.47) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8590728 | 0.80 | ALDH1A1 (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL907576 | 0.80 | TPMT (0.56) | TUBB1MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL27417353 | 0.79 | MAPT (0.54) | TUBB1MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL290542 | 0.79 | LMNA (0.69) | TUBB1MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL24147880 | 0.79 | TUBB1 (0.49) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110526854-B | Alpha, beta-unsaturated ketone derivative, preparation method and application thereof as medicine | 宁夏医科大学 | 2023-12-15 | — | — | CN | disclosed |
| EP-2942345-B1 | 3,4,5-TRIMETHOXYSTYRYLARYLAMINOPROPENONES FOR THE TREATMENT OF CANCER | COUNCIL SCIENT IND RES (IN) | 2018-03-28 | — | — | EP | disclosed |