Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.42 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18482098 | 0.83 | PTPN1 (0.50) | PTPN1SMN1; SMN2MAPTRAB9ATSHR | |
| SCHEMBL4302772 | 0.81 | LCK (0.59) | PTPN1SMN1; SMN2MAPTRAB9ATSHR | |
| SCHEMBL16163270 | 0.80 | PTPN1 (0.48) | PTPN1SMN1; SMN2MAPTRAB9ATSHR | |
| SCHEMBL21635979 | 0.79 | KDM4E (0.65) | PTPN1SMN1; SMN2MAPTRAB9ATSHR | |
| SCHEMBL28257934 | 0.79 | PTPN1 (0.57) | PTPN1SMN1; SMN2MAPTRAB9ATSHR | |
| SCHEMBL16163314 | 0.79 | SMN1; SMN2 (0.56) | PTPN1SMN1; SMN2MAPTRAB9ATSHR | |
| SCHEMBL16163313 | 0.79 | SMN1; SMN2 (0.56) | PTPN1SMN1; SMN2MAPTRAB9ATSHR | |
| SCHEMBL9829761 | 0.77 | TUBB1 (0.56) | MAPTALDH1A1TNFRSF1APKML3MBTL1 | |
| SCHEMBL16163163 | 0.77 | PTPN1 (0.54) | PTPN1SMN1; SMN2MAPTRAB9ATSHR | |
| SCHEMBL20007016 | 0.77 | HMGCR (0.56) | PTPN1SMN1; SMN2MAPTRAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2942345-B1 | 3,4,5-TRIMETHOXYSTYRYLARYLAMINOPROPENONES FOR THE TREATMENT OF CANCER | COUNCIL SCIENT IND RES (IN) | 2018-03-28 | — | — | EP | disclosed |