Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5535276 | 0.84 | KMT2A (0.62) | ALDH1A1TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL3977460 | 0.76 | HTT (0.65) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12585052 | 0.75 | MAPK1 (0.79) | ALDH1A1ALOX12TSHRKMT2AHPGD | |
| SCHEMBL4604079 | 0.75 | GABRA5 (0.49) | ALDH1A1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL20006966 | 0.74 | HPGD (0.67) | ALDH1A1ALOX12TSHRPOLBMEN1 | |
| SCHEMBL13501815 | 0.74 | ALDH1A1 (0.84) | ALDH1A1ALOX12TSHRHPGDMAPK1 | |
| SCHEMBL13501814 | 0.74 | ALDH1A1 (0.68) | ALDH1A1ALOX12TSHRPOLBMEN1 | |
| SCHEMBL4248633 | 0.74 | HTT (0.61) | ALDH1A1KMT2ASMN1; SMN2HTTLMNA | |
| SCHEMBL3975394 | 0.74 | HTT (0.61) | ALDH1A1KMT2ASMN1; SMN2HTTLMNA | |
| SCHEMBL4974673 | 0.74 | MAPK14 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055235-A1 | ISOXAZOLE-AMIDES FOR TREATING CARDIAC DISEASES | UNIVERSITY OF HELSINKI (FI) | 2018-03-29 | — | — | WO | disclosed |