Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6620113 | 0.85 | HTT (0.67) | HTTLMNAMAPK1RAB9ATUBB1 | |
| SCHEMBL30307376 | 0.84 | CYP1A2 (0.63) | LMNAMAPK1ABCG2MAPTALDH1A1 | |
| SCHEMBL547153 | 0.84 | CYP1A2 (0.63) | LMNAMAPK1ABCG2MAPTALDH1A1 | |
| SCHEMBL9054359 | 0.82 | LMNA (0.63) | HTTLMNAMAPK1RAB9ATUBB1 | |
| SCHEMBL16955580 | 0.81 | HTT (0.57) | HTTLMNAMAPK1RAB9ATUBB1 | |
| SCHEMBL28643734 | 0.81 | TUBB1 (0.55) | RAB9ATUBB1ABCG2ALDH1A1MEN1 | |
| SCHEMBL5426648 | 0.81 | HTT (0.71) | HTTLMNAMAPK1RAB9ATUBB1 | |
| SCHEMBL9806817 | 0.81 | LMNA (0.61) | HTTLMNAMAPK1RAB9ATUBB1 | |
| SCHEMBL9806815 | 0.81 | LMNA (0.61) | HTTLMNAMAPK1RAB9ATUBB1 | |
| SCHEMBL726699 | 0.81 | LMNA (0.66) | HTTLMNAMAPK1RAB9ATUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2942345-B1 | 3,4,5-TRIMETHOXYSTYRYLARYLAMINOPROPENONES FOR THE TREATMENT OF CANCER | COUNCIL SCIENT IND RES (IN) | 2018-03-28 | — | — | EP | disclosed |