Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6620113 | 0.97 | HTT (0.67) | LMNAHTTMAPK1RAB9ATUBB1 | |
| SCHEMBL8887041 | 0.89 | HTT (0.58) | LMNAHTTMAPK1RAB9AMAPT | |
| SCHEMBL20007006 | 0.82 | HTT (0.65) | LMNAHTTMAPK1RAB9ATUBB1 | |
| SCHEMBL4281872 | 0.81 | CYP1A2 (0.66) | LMNAMAPK1MAPTABCG2ALDH1A1 | |
| SCHEMBL3606868 | 0.80 | MAPT (0.76) | LMNAHTTMAPK1RAB9ATUBB1 | |
| SCHEMBL3606864 | 0.80 | MAPT (0.76) | LMNAHTTMAPK1RAB9ATUBB1 | |
| Water SCHEMBL29060509 | 0.80 | CYP1A2 (0.63) | LMNAMAPK1MAPTABCG2ALDH1A1 | |
| Water SCHEMBL30477093 | 0.80 | CYP1A2 (0.63) | LMNAMAPK1MAPTABCG2ALDH1A1 | |
| SCHEMBL726699 | 0.79 | LMNA (0.66) | LMNAHTTMAPK1RAB9ATUBB1 | |
| SCHEMBL9806815 | 0.79 | LMNA (0.61) | LMNAHTTMAPK1RAB9ATUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996007658-A1 | PYRAZOLO[3,4-g]QUINOXALINE COMPOUNDS WHICH INHIBIT PDGF RECEPTOR PROTEIN TYROSINE KINASE | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-03-14 | — | — | WO | disclosed |