Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.52 |
| ▸ | CFTR | P13569 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL11786715 | 0.98 | MAPT (0.52) | ALDH1A1HSD17B10CFTRMAPTGAA | |
| SCHEMBL11646833 | 0.87 | CA1 (0.50) | ALDH1A1HSD17B10CFTRMAPTGAA | |
| SCHEMBL10533216 | 0.84 | ALDH1A1 (0.43) | ALDH1A1HSD17B10MAPTGAATSHR | |
| SCHEMBL11004717 | 0.83 | ALDH1A1 (0.55) | ALDH1A1HSD17B10CFTRMAPTGAA | |
| Methacrylic Acid SCHEMBL8010054 | 0.82 | MAPT (0.53) | ALDH1A1HSD17B10CFTRMAPTGAA | |
| SCHEMBL1885621 | 0.82 | MAPT (0.60) | ALDH1A1HSD17B10CFTRMAPTGAA | |
| SCHEMBL13468038 | 0.81 | MMP2 (0.39) | ALDH1A1HSD17B10CFTRMAPTGAA | |
| SCHEMBL10487065 | 0.81 | MAPT (0.50) | ALDH1A1HSD17B10CFTRMAPTGAA | |
| SCHEMBL28440125 | 0.79 | KDM4E (0.48) | ALDH1A1HSD17B10MAPTGAATSHR | |
| SCHEMBL13465392 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HSD17B10CFTRMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2942345-B1 | 3,4,5-TRIMETHOXYSTYRYLARYLAMINOPROPENONES FOR THE TREATMENT OF CANCER | COUNCIL SCIENT IND RES (IN) | 2018-03-28 | — | — | EP | disclosed |