Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19223347 | 0.86 | TDP1 (0.46) | TDP1KMT2AMEN1MGAMGAA | |
| SCHEMBL4613905 | 0.81 | TDP1 (0.50) | TDP1KMT2AMEN1MGAMGAA | |
| SCHEMBL15726352 | 0.81 | TDP1 (0.41) | TDP1KMT2AMEN1MGAMGAA | |
| SCHEMBL19441166 | 0.81 | GAA (0.39) | KMT2AMEN1MGAMGAASI | |
| Dimethylamine SCHEMBL15711059 | 0.80 | TDP1 (0.43) | TDP1KMT2AMEN1MGAMGAA | |
| SCHEMBL18307599 | 0.79 | CA1 (0.46) | KMT2AMEN1MGAMGAASI | |
| SCHEMBL8535256 | 0.78 | ADH1B (0.41) | TDP1KMT2AMEN1MGAMGAA | |
| SCHEMBL15033661 | 0.78 | CPB2 (0.38) | KMT2AMEN1MGAMGAASI | |
| SCHEMBL11655565 | 0.77 | TDP1 (0.56) | TDP1KMT2AMEN1MGAMGAA | |
| SCHEMBL7659602 | 0.77 | TDP1 (0.56) | TDP1KMT2AMEN1MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2740738-B1 | PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASE, PREPARATION METHODS AND USES THEREOF | BEIJING FSWELCOME TECH DEVELOPMENT CO LTD (CN) | 2018-03-28 | — | — | EP | disclosed |