Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513541 | 0.72 | GAA (0.44) | ALDH1A1CYP2C19TYMP | |
| SCHEMBL17787656 | 0.68 | TYMP (0.38) | ALDH1A1CYP2C19TYMP | |
| SCHEMBL13435344 | 0.64 | CYP3A4 (0.47) | ALDH1A1TYMPCYP3A4 | |
| SCHEMBL31243823 | 0.64 | CTDSP1 (0.36) | ALDH1A1CTDSP1TYMP | |
| SCHEMBL14544303 | 0.63 | BRD4 (0.39) | — | |
| SCHEMBL22161585 | 0.63 | — | — | |
| SCHEMBL28202618 | 0.61 | UPP1 (0.36) | ALDH1A1CYP2C19 | |
| SCHEMBL29341072 | 0.61 | CTDSP1 (0.30) | CTDSP1 | |
| SCHEMBL9769540 | 0.59 | ALDH1A1 (0.37) | ALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL6673604 | 0.59 | EPHX2 (0.42) | ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432496-B1 | CONTROL OF URIC ACID HOMEOSTASIS | ETH ZUERICH (CH) | 2018-03-28 | — | — | EP | disclosed |