Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | TPI1 | P60174 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL6687413 | 0.95 | EPHX2 (0.40) | EPHX2ALDH1A1CYP2C19KDM4EGAA | |
| SCHEMBL9412532 | 0.79 | KDM4E (0.51) | EPHX2ALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL10667165 | 0.79 | KDM4E (0.63) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL15075767 | 0.78 | KDM4E (0.46) | EPHX2ALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL9430532 | 0.77 | KDM4E (0.70) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL9847038 | 0.75 | ALDH1A1 (0.34) | ALDH1A1CYP2C19LMNAMAPTCHRNB2 | |
| SCHEMBL10699801 | 0.74 | KDM4E (0.68) | ALDH1A1CYP2C19KDM4EGAAKMT2A | |
| SCHEMBL6886919 | 0.74 | EPHX2 (0.41) | EPHX2ALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL17682245 | 0.72 | EPHX2 (0.44) | EPHX2ALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL19036786 | 0.72 | KDM4E (0.52) | EPHX2ALDH1A1KDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463727-A2 | HETEROCYCLIC COMPOUNDS THAT ARE INHIBITORS OF THE ENZYME DPP-IV | NOVO NORDISK A/S (DK) | 2004-10-06 | — | — | EP | disclosed |
| US-20030199528-A1 | Hetrocyclic compounds that are inhibitors of the enzyme DPP-IV | NOVO NORDISK A/S (DK) | 2003-10-23 | — | — | US | disclosed |
| WO-2003024965-A2 | HETEROCYCLIC COMPOUNDS THAT ARE INHIBITORS OF THE ENZYME DPP-IV | NOVO NORDISK A/S (DK) | 2003-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199528-A1 | Hetrocyclic compounds that are inhibitors of the enzyme DPP-IV | DPP4, DPP7, DPP3 | EPHX2 305/4885ALDH1A1 500/4885CYP2C19 481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.