Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008361 | 0.67 | KMT2A (0.35) | KDM4EALDH1A1GAA | |
| SCHEMBL20008379 | 0.60 | — | — | |
| SCHEMBL20008388 | 0.59 | KDM4E (0.31) | KDM4E | |
| SCHEMBL20008394 | 0.59 | RAB9A (0.33) | KDM4EALDH1A1GAA | |
| SCHEMBL20008172 | 0.58 | — | — | |
| SCHEMBL20008142 | 0.58 | — | — | |
| SCHEMBL20008513 | 0.57 | RAF1 (0.61) | — | |
| SCHEMBL8511208 | 0.55 | POLB (0.53) | KDM4EALDH1A1 | |
| SCHEMBL20008794 | 0.55 | RAF1 (0.50) | — | |
| SCHEMBL3351392 | 0.54 | CYP2A6 (0.42) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |