Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.33 |
| ▸ | GAA | P10253 | 6/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008158 | 0.67 | KDM4E (0.32) | ALDH1A1KDM4EGAA | |
| SCHEMBL20008169 | 0.62 | PABPC1 (0.34) | PABPC1 | |
| SCHEMBL13716023 | 0.58 | APP (0.35) | KMT2AALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL20008304 | 0.57 | ALOX5 (0.41) | KMT2AALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL21954796 | 0.56 | SMN1; SMN2 (0.38) | KMT2AALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL24016965 | 0.56 | SMN1; SMN2 (0.35) | ALDH1A1SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL14621614 | 0.55 | POLB (0.56) | KMT2AALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL21020940 | 0.55 | EGFR (0.34) | ALDH1A1MAPTLMNA | |
| SCHEMBL24934242 | 0.55 | ALDH1A1 (0.34) | ALDH1A1MAPTLMNA | |
| SCHEMBL13855006 | 0.55 | ALDH1A1 (0.45) | KMT2AALDH1A1SMN1; SMN2KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |