Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008306 | 0.88 | — | — | |
| SCHEMBL20008531 | 0.82 | — | — | |
| SCHEMBL20008393 | 0.81 | KCNH2 (0.31) | — | |
| SCHEMBL20008173 | 0.72 | — | — | |
| SCHEMBL20008315 | 0.71 | — | — | |
| SCHEMBL20008186 | 0.69 | — | — | |
| SCHEMBL24269539 | 0.68 | ALDH1A1 (0.47) | IMPDH2ALDH1A1 | |
| SCHEMBL20008390 | 0.68 | — | — | |
| SCHEMBL20009423 | 0.66 | MEN1 (0.36) | — | |
| SCHEMBL14046649 | 0.64 | ALDH1A1 (0.46) | IMPDH2IMPDH1ALDH1A1EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |