SCHEMBL2000825

SCHEMBL2000825

COC(=O)c1ccc2cc(C(=O)O)ccc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.67
PTPN11 Q06124 2/20 0.60
KDM6B O15054 1/20 0.59
KDM5C P41229 1/20 0.59
KDM4C Q9H3R0 1/20 0.59
KDM2A Q9Y2K7 1/20 0.59
KDM3A Q9Y4C1 1/20 0.59
LCK P06239 1/20 0.57
CA1 P00915 5/20 0.55
CA2 P00918 5/20 0.55
CA12 O43570 3/20 0.55
CA7 P43166 3/20 0.55
CA9 Q16790 3/20 0.55
CA14 Q9ULX7 3/20 0.55
XDH P47989 1/20 0.55
CYP19A1 P11511 1/20 0.53
CYP11B1 P15538 1/20 0.53
CYP11B2 P19099 1/20 0.53
TSHR P16473 1/20 0.52
ALOX15 P16050 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29809867 1.00 KDM4E (0.67) KDM4EPTPN11KDM6BKDM5CKDM4C
Hydrochloric Acid SCHEMBL8923197 0.98 KDM4E (0.65) KDM4EPTPN11KDM6BKDM5CKDM4C
SCHEMBL3018277 0.94 KDM4E (0.59) KDM4EPTPN11KDM6BKDM5CKDM4C
SCHEMBL7744919 0.93 KDM4E (0.59) KDM4EPTPN11KDM6BKDM5CKDM4C
SCHEMBL29365729 0.92 PTPN11 (0.68) KDM4EPTPN11LCKCA1CA2
SCHEMBL69025 0.92 PTPN11 (0.68) KDM4EPTPN11LCKCA1CA2
SCHEMBL8732524 0.90 PTPN11 (0.66) KDM4EPTPN11LCKCA1CA2
SCHEMBL9979782 0.88 PTPN11 (0.64) KDM4EPTPN11LCKCA1CA2
Methoxymethane SCHEMBL6861468 0.87 KDM4E (0.77) KDM4ECA1CA2CA12CA7
SCHEMBL9361547 0.86 KDM4E (0.51) KDM4EPTPN11KDM6BKDM5CKDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112876359-B Preparation method of dimethyl 2, 6-naphthalene dicarboxylate 上海中化科技有限公司 2022-11-01 CN claimed
CN-217661568-U 2,6-dimethyl naphthanate refining device 煤炭科学技术研究院有限公司 2022-10-28 CN claimed
CN-115246923-A Wide-color-gamut high-performance fluorescent copolyester and synthesis method and application thereof 中国科学院化学研究所 2022-10-28 CN claimed
CN-112876359-A Preparation method of dimethyl 2, 6-naphthalenedicarboxylate 上海中化科技有限公司 2021-06-01 CN claimed
CN-108976404-A The poly- 2,6- (ethylene naphthalate) and its preparation method of modified by cardanol 沈阳建筑大学 2018-12-11 CN claimed
US-6755991-B2 ESPECIALLY 2,6-NAPHTHALENEDICARBOXYLIC ACID MIXED WITH 6-FORMYL-2-NAPHTHOIC ACID, 6-METHOXYCARBONYL-2-NAPHTHOIC ACID OR TRIMELLITIC ACID; ALKALI METAL COMPOUND KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2004-06-29 US claimed
EP-0877012-B1 Process for the production of high-purity dimethyl 2,6-naphthalenedicarboxylate and naphthalenedicarboxylic acid MITSUBISHI GAS CHEMICAL CO (JP) 2003-04-16 EP claimed
US-20020045728-A1 Aromatic dicarboxylic acid composition and liquid crystalline polyester resin made from the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO 2002-04-18 US claimed
EP-0877012-A2 Process for the production of high-purity dimethyl 2,6-naphthalenedicarboxylate and naphthalenedicarboxylic acid MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1998-11-11 EP claimed
US-5371302-A Adding specified soluble compounds to molten bisphenol A, granulating NIPPON STEEL CHEMICAL CO., LTD. (JP) 1994-12-06 US claimed
EP-0392942-B1 Preparation of poly(ethylene-2,6-naphthalene dicarboxylate) from dimethyl-2,6-naphthalene dicarboxylate and methyl hydrogen 2,6-naphthalene dicarboxylate EASTMAN KODAK CO (US) 1994-03-23 EP claimed
EP-0467950-A1 PREPARATION OF POLY(ETHYLENE-2,6-NAPHTHALENE DICARBOXYLATE) FROM DIMETHYL-2,6-NAPHTHALENE DICARBOXYLATE AND METHYL HYDROGEN 2,6-NAPHTHALENE DICARBOXYLATE EASTMAN KODAK COMPANY (US) 1992-01-29 EP claimed
US-5013820-A Preparation of poly(ethlene-2,6-naphthalene dicarboxylate) from dimethyl-2,6-naphthalene dicarboxylate and methyl hydrogen 2,6-naphthalene dicarboxylate EASTMAN KODAK COMPANY (US) 1991-05-07 US claimed
WO-1990012048-A1 PREPARATION OF POLY(ETHYLENE-2,6-NAPHTHALENE DICARBOXYLATE) FROM DIMETHYL-2,6-NAPHTHALENE DICARBOXYLATE AND METHYL HYDROGEN 2,6-NAPHTHALENE DICARBOXYLATE EASTMAN KODAK COMPANY (US) 1990-10-18 WO claimed
EP-0392942-A1 Preparation of poly(ethylene-2,6-naphthalene dicarboxylate) from dimethyl-2,6-naphthalene dicarboxylate and methyl hydrogen 2,6-naphthalene dicarboxylate EASTMAN CHEMICAL COMPANY (US) 1990-10-17 EP claimed
US-4048021-A VACUUM DISTILLATION TEIJIN LIMITED (JA) 1977-09-13 US claimed
JP-1024852-A None JP disclosed
JP-6220174-A None JP disclosed
US-3951905-A ANTIMONY CONTAINING PARTICLES TORAY INDUSTRIES, INC. (JA) 1976-04-20 US disclosed
US-3935166-A OR 2,7 NAPHTHALENE DICARBOXYLIC ACIDADHESIVE TEIJIN LIMITED (JA) 1976-01-27 US disclosed