SCHEMBL7744919

SCHEMBL7744919

COC(=O)c1cccc(C(=O)OC)c1.O=C(O)c1ccc2cc(C(=O)O)ccc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.59
PTPN11 Q06124 2/20 0.58
KDM6B O15054 1/20 0.57
KDM5C P41229 1/20 0.57
KDM4C Q9H3R0 1/20 0.57
KDM2A Q9Y2K7 1/20 0.57
KDM3A Q9Y4C1 1/20 0.57
PLAU P00749 7/20 0.56
TSHR P16473 1/20 0.55
RAB9A P51151 1/20 0.51
LCK P06239 1/20 0.51
CYP19A1 P11511 1/20 0.51
CYP11B1 P15538 1/20 0.51
CYP11B2 P19099 1/20 0.51
PLAT P00750 2/20 0.50
LOXL2 Q9Y4K0 1/20 0.50
PLG P00747 1/20 0.50
ALOX15 P16050 1/20 0.50
HTT P42858 1/20 0.50
CYSLTR1 Q9Y271 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7744907 0.93 PTPN11 (0.65) PTPN11PLAUTSHRRAB9ALCK
SCHEMBL29809867 0.93 KDM4E (0.67) KDM4EPTPN11KDM6BKDM5CKDM4C
SCHEMBL2000825 0.93 KDM4E (0.67) KDM4EPTPN11KDM6BKDM5CKDM4C
Hydrochloric Acid SCHEMBL8923197 0.91 KDM4E (0.65) KDM4EPTPN11KDM6BKDM5CKDM4C
SCHEMBL30262601 0.91 KDM4E (0.66) KDM4EKDM6BKDM5CKDM4CKDM2A
Isophthalic Acid SCHEMBL5551894 0.91 KDM4E (0.66) KDM4EKDM6BKDM5CKDM4CKDM2A
SCHEMBL39797 0.91 KDM4E (0.66) KDM4EKDM6BKDM5CKDM4CKDM2A
Water SCHEMBL28842117 0.89 KDM4E (0.64) KDM4EKDM6BKDM5CKDM4CKDM2A
Hydrochloric Acid SCHEMBL5454358 0.89 KDM4E (0.64) KDM4EKDM6BKDM5CKDM4CKDM2A
Terephthalic Acid SCHEMBL27517516 0.89 TSHR (0.63) KDM4EKDM6BKDM5CKDM4CKDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6232054-B1 TEAR STRENGTH IN THE TRANSVERSE DIRECTION (TD) OF 10 TO 100 G, A BREAK STRENGTH IN TD OF 10 TO 40 KG/MM.2, A BREAK STRENGTH IN THE MACHINE DIRECTION (MD) OF 2 TO 25 KG/MM.2 AND A THICKNESS UNEVENNESS IN MD OF 0 TO 8 MU.M. FUJI PHOTO FILM CO., LTD. (JP) 2001-05-15 US disclosed