Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 19/20 | 0.42 |
| ▸ | BRAF | P15056 | 18/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008167 | 0.92 | RAF1 (0.42) | RAF1BRAFKMO | |
| SCHEMBL20008291 | 0.89 | RAF1 (0.45) | RAF1BRAF | |
| SCHEMBL20009446 | 0.77 | RAF1 (0.41) | RAF1BRAF | |
| SCHEMBL20008331 | 0.72 | RAF1 (0.43) | RAF1BRAF | |
| SCHEMBL26815890 | 0.68 | RAF1 (0.65) | RAF1BRAF | |
| SCHEMBL20008486 | 0.66 | CNR2 (0.45) | RAF1BRAFKMO | |
| SCHEMBL20008259 | 0.65 | RAF1 (0.38) | RAF1BRAF | |
| SCHEMBL20008469 | 0.65 | CNR2 (0.38) | RAF1BRAF | |
| SCHEMBL20008157 | 0.64 | RAF1 (0.49) | RAF1BRAF | |
| SCHEMBL16094949 | 0.64 | RAF1 (0.54) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |