Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.32 |
| ▸ | SLC9A3 | P48764 | 2/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16938474 | 0.68 | ALOX5 (0.49) | ALOX5PTGS1PTGS2ALDH1A1LMNA | |
| SCHEMBL11790340 | 0.66 | ALOX5 (0.55) | ALOX5PTGS1PTGS2ALDH1A1LMNA | |
| SCHEMBL11790300 | 0.66 | ALOX5 (0.55) | ALOX5PTGS1PTGS2ALDH1A1LMNA | |
| SCHEMBL23015440 | 0.66 | ALOX5 (0.43) | ALOX5PTGS1PTGS2ALDH1A1GABRA1 | |
| SCHEMBL9211398 | 0.66 | ALOX5 (0.50) | ALOX5PTGS1PTGS2ALDH1A1LMNA | |
| SCHEMBL9211406 | 0.66 | ALOX5 (0.50) | ALOX5PTGS1PTGS2ALDH1A1LMNA | |
| SCHEMBL11860086 | 0.65 | ALOX5 (0.53) | ALOX5PTGS1PTGS2ALDH1A1LMNA | |
| SCHEMBL11860111 | 0.65 | ALOX5 (0.53) | ALOX5PTGS1PTGS2ALDH1A1LMNA | |
| SCHEMBL11333581 | 0.64 | ALOX5 (0.49) | ALOX5PTGS1PTGS2ALDH1A1LMNA | |
| SCHEMBL11333577 | 0.64 | ALOX5 (0.49) | ALOX5PTGS1PTGS2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |