SCHEMBL9211398

SCHEMBL9211398

CC/C=C/c1cc(C)ccc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.50
PTGS1 P23219 1/20 0.50
PTGS2 P35354 1/20 0.50
ALDH1A1 P00352 4/20 0.41
PDE5A O76074 2/20 0.40
TAAR1 Q96RJ0 1/20 0.39
LMNA P02545 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
NPSR1 Q6W5P4 2/20 0.39
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39
HSP90AA1 P07900 1/20 0.39
ALOX12 P18054 2/20 0.37
GAA P10253 1/20 0.34
SRC P12931 1/20 0.33
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9211406 1.00 ALOX5 (0.50) ALOX5PTGS1PTGS2ALDH1A1PDE5A
SCHEMBL7209879 0.84 PDE5A (0.48) ALOX5PTGS1PTGS2ALDH1A1PDE5A
SCHEMBL8819996 0.83 PDE5A (0.40) ALOX5PTGS1PTGS2ALDH1A1PDE5A
SCHEMBL5837442 0.83 PDE5A (0.40) ALOX5PTGS1PTGS2ALDH1A1PDE5A
SCHEMBL11333581 0.82 ALOX5 (0.49) ALOX5PTGS1PTGS2ALDH1A1PDE5A
SCHEMBL2089038 0.82 ALOX5 (0.49) ALOX5PTGS1PTGS2ALDH1A1PDE5A
SCHEMBL11333577 0.82 ALOX5 (0.49) ALOX5PTGS1PTGS2ALDH1A1PDE5A
SCHEMBL2089036 0.82 ALOX5 (0.49) ALOX5PTGS1PTGS2ALDH1A1PDE5A
SCHEMBL1610588 0.80 ALOX5 (0.46) ALOX5PTGS1PTGS2ALDH1A1TAAR1
SCHEMBL2092828 0.80 ALOX5 (0.47) ALOX5PTGS1PTGS2ALDH1A1PDE5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7017879-A None JP disclosed
JP-7309789-A None JP disclosed
JP-H07309789-A PRODUCTION OF 2,6-DIMETHYLNAPHTHALENE MITSUBISHI CHEM CORP 1995-11-28 JP disclosed
JP-H0717879-A PRODUCTION OF 2,6-DIMETHYLNAPHTHALENE MITSUBISHI CHEM CORP 1995-01-20 JP disclosed