Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289307 | 0.88 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTNPC1HTT | |
| SCHEMBL2291232 | 0.88 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTNPC1HTT | |
| SCHEMBL2294503 | 0.80 | PARP10 (0.55) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL2294476 | 0.79 | SOD1 (0.55) | ALDH1A1SMN1; SMN2MAPTNPC1HTT | |
| SCHEMBL18171756 | 0.78 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MAPTNPC1HTT | |
| SCHEMBL19483249 | 0.78 | MRGPRX4 (0.55) | SMN1; SMN2MAPTNPC1RAB9ALMNA | |
| SCHEMBL2293075 | 0.76 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTNPC1HTT | |
| SCHEMBL2291817 | 0.76 | IDO1 (0.42) | ALDH1A1SMN1; SMN2MAPTNPC1HTT | |
| SCHEMBL11168946 | 0.74 | MRGPRX4 (0.48) | SMN1; SMN2MAPTRAB9ANPSR1LMNA | |
| SCHEMBL12772153 | 0.74 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2MAPTNPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10252967-B2 | Bridged bi-aromatic ligands and transition metal compounds prepared therefrom | UNIVATION TECHNOLOGIES, LLC (US) | 2019-04-09 | — | — | US | disclosed |
| EP-3286202-B1 | BRIDGED BI-AROMATIC LIGANDS AND TRANSITION METAL COMPOUNDS PREPARED THEREFROM | UNIVATION TECH LLC (US) | 2019-03-13 | — | — | EP | disclosed |
| US-20180086685-A1 | BRIDGED BI-AROMATIC LIGANDS AND TRANSITION METAL COMPOUNDS PREPARED THEREFROM | UNIVATION TECHNOLOGIES, LLC (US) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086685-A1 | BRIDGED BI-AROMATIC LIGANDS AND TRANSITION METAL COMPOUNDS PREPARED THEREFROM | WEE2, WEE1, AHR | ALDH1A1 1250/4885SMN1; SMN2 4622/4885MAPT 1075/4885 |
| US-10252967-B2 | Bridged bi-aromatic ligands and transition metal compounds prepared therefrom | WEE2, WEE1, AHR | ALDH1A1 1250/4885SMN1; SMN2 4622/4885MAPT 1075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.