Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20009832 | 0.67 | — | — | |
| SCHEMBL20008286 | 0.65 | — | — | |
| SCHEMBL2424622 | 0.61 | HTT (0.49) | — | |
| SCHEMBL20008405 | 0.61 | OPRK1 (0.32) | PIK3C3 | |
| SCHEMBL20008321 | 0.60 | OPRK1 (0.32) | PIK3C3 | |
| SCHEMBL24080970 | 0.60 | NOS3 (0.42) | PIK3C3 | |
| SCHEMBL30636902 | 0.60 | HTT (0.50) | — | |
| SCHEMBL20008573 | 0.59 | — | — | |
| SCHEMBL5163581 | 0.59 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL31165542 | 0.57 | HTT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |