Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008405 | 0.80 | OPRK1 (0.32) | — | |
| SCHEMBL17893277 | 0.58 | PDK1 (0.44) | PDK1 | |
| SCHEMBL8425994 | 0.58 | PDK1 (0.48) | PDK1 | |
| SCHEMBL18528191 | 0.58 | PDK1 (0.44) | PDK1 | |
| SCHEMBL23710200 | 0.58 | TSHR (0.54) | PDK1 | |
| SCHEMBL14971324 | 0.58 | HPGD (0.47) | PDK1 | |
| SCHEMBL22732900 | 0.58 | HPGD (0.47) | PDK1 | |
| SCHEMBL22732982 | 0.58 | HPGD (0.47) | PDK1 | |
| SCHEMBL23710005 | 0.58 | TSHR (0.54) | PDK1 | |
| SCHEMBL19002271 | 0.58 | TSHR (0.54) | PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |