Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008162 | 0.76 | CRHR1 (0.35) | CRHR1 | |
| SCHEMBL20008752 | 0.73 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL20008148 | 0.72 | CRHR1 (0.32) | CRHR1 | |
| SCHEMBL20008333 | 0.72 | RAF1 (0.32) | CRHR1 | |
| SCHEMBL20008353 | 0.71 | CRHR1 (0.32) | CRHR1 | |
| SCHEMBL20009334 | 0.67 | — | — | |
| SCHEMBL20008458 | 0.67 | CRHR1 (0.31) | CRHR1 | |
| SCHEMBL20008141 | 0.63 | BRAF (0.31) | CRHR1 | |
| SCHEMBL20008703 | 0.62 | CRHR1 (0.35) | CRHR1 | |
| SCHEMBL20008772 | 0.62 | BRAF (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |