Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 3/20 | 0.32 |
| ▸ | BRAF | P15056 | 3/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008162 | 0.84 | CRHR1 (0.35) | CRHR1 | |
| SCHEMBL20008752 | 0.81 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL20008148 | 0.80 | CRHR1 (0.32) | CRHR1 | |
| SCHEMBL20008353 | 0.78 | CRHR1 (0.32) | CRHR1 | |
| SCHEMBL20008423 | 0.72 | CRHR1 (0.34) | CRHR1 | |
| SCHEMBL20008141 | 0.71 | BRAF (0.31) | BRAFCRHR1 | |
| SCHEMBL20008776 | 0.70 | CRHR1 (0.36) | CRHR1 | |
| SCHEMBL20008772 | 0.70 | BRAF (0.31) | BRAF | |
| SCHEMBL20008703 | 0.70 | CRHR1 (0.35) | RAF1BRAFCRHR1 | |
| SCHEMBL23654081 | 0.67 | RARA (0.32) | RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |