Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008517 | 0.69 | RAF1 (0.43) | RAF1BRAF | |
| SCHEMBL20008426 | 0.66 | RAF1 (0.40) | RAF1BRAF | |
| SCHEMBL20008376 | 0.65 | RAF1 (0.42) | RAF1BRAF | |
| SCHEMBL20008784 | 0.62 | BTK (0.34) | RAF1 | |
| SCHEMBL20008527 | 0.62 | RAF1 (0.36) | RAF1BRAF | |
| SCHEMBL20008380 | 0.61 | RAF1 (0.48) | RAF1BRAF | |
| SCHEMBL20008454 | 0.60 | NPC1 (0.31) | — | |
| SCHEMBL20008594 | 0.60 | RAF1 (0.47) | RAF1BRAF | |
| SCHEMBL20008387 | 0.59 | RAF1 (0.45) | RAF1BRAF | |
| SCHEMBL20009306 | 0.59 | RAF1 (0.36) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |