Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008473 | 0.66 | RAF1 (0.41) | RAF1BRAF | |
| SCHEMBL20009211 | 0.64 | RAF1 (0.49) | RAF1BRAF | |
| SCHEMBL20008336 | 0.64 | RAF1 (0.40) | RAF1BRAF | |
| SCHEMBL20008414 | 0.63 | RAF1 (0.45) | RAF1BRAF | |
| SCHEMBL20008243 | 0.61 | BRAF (0.44) | RAF1BRAF | |
| SCHEMBL20008240 | 0.60 | RAF1 (0.43) | RAF1BRAF | |
| SCHEMBL20867961 | 0.60 | PKM (0.52) | RAF1BRAF | |
| SCHEMBL19529299 | 0.59 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL16100718 | 0.58 | RAF1 (1.00) | RAF1BRAF | |
| SCHEMBL20008169 | 0.58 | PABPC1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |