Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 17/20 | 0.51 |
| ▸ | BRAF | P15056 | 17/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095240 | 0.80 | RAF1 (0.59) | RAF1BRAFALDH1A1 | |
| SCHEMBL20008620 | 0.75 | RAF1 (0.54) | RAF1BRAF | |
| SCHEMBL25594314 | 0.73 | RAF1 (0.63) | RAF1BRAF | |
| SCHEMBL20008328 | 0.72 | CNR2 (0.48) | RAF1BRAFALDH1A1 | |
| SCHEMBL23299892 | 0.70 | ALDH1A1 (0.64) | RAF1BRAFALDH1A1 | |
| SCHEMBL17322817 | 0.70 | PIK3R1 (0.75) | RAF1BRAFPIK3R1ALDH1A1 | |
| SCHEMBL26783363 | 0.69 | RAF1 (0.58) | RAF1BRAF | |
| SCHEMBL25594308 | 0.69 | RAF1 (0.53) | RAF1BRAFALDH1A1 | |
| SCHEMBL23299910 | 0.69 | NPY1R (0.51) | ALDH1A1NPY1RKCNH2 | |
| SCHEMBL17322800 | 0.68 | PIK3R1 (0.72) | RAF1BRAFPIK3R1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |