Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 6/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008789 | 0.86 | HDAC6 (0.53) | HDAC6BCHEPTGS2ESR1ESR2 | |
| SCHEMBL8192034 | 0.84 | PTGS2 (0.44) | HDAC6BCHEPTGS2ALDH1A1CYP1A2 | |
| SCHEMBL29617992 | 0.82 | HDAC6 (0.54) | HDAC6BCHEPTGS2ALDH1A1CYP1A2 | |
| SCHEMBL8183708 | 0.82 | HDAC6 (0.54) | HDAC6BCHEPTGS2ALDH1A1CYP1A2 | |
| SCHEMBL23555415 | 0.78 | HDAC6 (0.50) | HDAC6BCHEPTGS2ALDH1A1CYP1A2 | |
| SCHEMBL17278627 | 0.74 | HDAC6 (0.48) | HDAC6BCHEALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11988552 | 0.74 | EGFR (0.43) | ALDH1A1CYP3A4KDM4EHPGDMAPK1 | |
| SCHEMBL11988043 | 0.74 | PTGS2 (0.36) | HDAC6BCHEPTGS2KMT2A | |
| SCHEMBL9026535 | 0.74 | PTGS2 (0.73) | PTGS2ALDH1A1CYP3A4ESR1ESR2 | |
| SCHEMBL9026538 | 0.74 | PTGS2 (0.73) | PTGS2ALDH1A1CYP3A4ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180088123-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES | SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180088123-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES | ALB, EPCAM, ELAVL1 | HDAC6 671/4885BCHE 3946/4885PTGS2 3980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.