Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2495862 | 0.91 | CYP19A1 (0.39) | PTGS2HDAC6DUSP22BCHEMEN1 | |
| SCHEMBL8174042 | 0.85 | ALDH1A1 (0.35) | PTGS2HDAC6DUSP22BCHEMEN1 | |
| SCHEMBL20008792 | 0.84 | HDAC6 (0.50) | PTGS2HDAC6BCHEKMT2ACYP1A2 | |
| SCHEMBL11988552 | 0.81 | EGFR (0.43) | ALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL11988043 | 0.81 | PTGS2 (0.36) | PTGS2HDAC6DUSP22BCHEMEN1 | |
| SCHEMBL2501589 | 0.81 | NOX1 (0.49) | PTGS2MEN1KMT2ACYP19A1CYP11B2 | |
| SCHEMBL8183837 | 0.77 | PTGS2 (0.39) | PTGS2MEN1KMT2ACYP19A1CYP11B2 | |
| SCHEMBL8185276 | 0.76 | CYP2A6 (0.46) | HDAC6MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL13030816 | 0.76 | TRPM2 (0.33) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5486677 | 0.76 | TDP1 (0.42) | PTGS2MEN1KMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6083651-A | SOLUBLE IN POLYMERIC BINDERS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2000-07-04 | — | — | US | disclosed |
| US-5942615-A | GOOD SOLUBILITY IN BINDER POLYMERS, SENSITIVITY, AND LOW RESIDUAL POTENTIAL | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-08-24 | — | — | US | disclosed |